Protein Purification
MilliporeSigma™ Calbiochem™ InSolution™ Necrostatin-1
A cell-permeable, potent, and selective blocker of necroptosis (EC50 = 494nM in FADD-deficient Jurkat cells treated with TNF-α), a nonapoptotic necrotic cell death pathway mediated by death-domain receptors (DRs) that offers neuroprotection in a murine model of ischemic brain inj
MilliporeSigma™ Calbiochem™ SKP2 E3 Ligase Inhibitor IV
A cell-permeable inhibitor of SKP2-dependent p27Kip1 ubiquitination. Selectively induces the accumulation SCFSKP2 substrates in multiple myeloma RPMI 8226 cells.
MilliporeSigma™ Calbiochem™ Rac1 Inhibitor
Rac1 Inhibitor, CAS 1177865-17-6, is a cell-permeable, reversible inhibitor of Rac1 GDP/GTP exchange. Interferes with the interaction between Rac1 and Rac-specific GEFs Trio and Tiam1 (IC50 ≈50 μM).
MilliporeSigma™ Calbiochem™ IP6K Inhibitor
The IP6K Inhibitor, also referenced under CAS 519178-28-0, controls the biological activity of IP6K.
MilliporeSigma™ Calbiochem™ HDAC6 Inhibitor II, BRD9757
A cell-permeable, low molecular weight hydroxamate compound that acts as a potent histone deacetylase class IIb HDAC6-selective inhibitor (IC50 = 30nM), while inhibiting class I HDAC1/2/3/8 only at higher concentrations (IC50
MilliporeSigma™ Calbiochem™ NF-κB SN50M, Cell-Permeable Inactive Control Peptide
An inactive control for SN50 peptide.
MilliporeSigma™ Calbiochem™ FITC, Isomer I
Used to label antibodies or proteins.
MilliporeSigma™ Calbiochem™ PKA Inhibitor 5-24
The PKA Inhibitor 5-24, also referenced under CAS 99534-03-9, controls the biological activity of PKA.
MilliporeSigma™ Calbiochem™ Amyloid Precursor Protein β-Secretase Inhibitor
The Amyloid Precursor Protein β-Secretase Inhibitor controls the biological activity of Amyloid Precursor Protein β-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ InSolution™ OM99-2
An eight residue peptidomimetic, tight binding transition-state analog inhibitor of human brain memapsin 2.
MilliporeSigma™ Calbiochem™ PKCε Translocation Inhibitor Peptide
The PKCε Translocation Inhibitor Peptide, Negative Control controls the biological activity of PKCε. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ TMPyP4
A potent inhibitor of human telomerase (IC50 = 6.5 μM).
Cytiva HiScreen Phenyl FF (High Sub)
HiScreen Phenyl FF (high sub) columns are prepacked with Phenyl Sepharose 6 Fast Flow hydrophobic interaction chromatography (HIC) media. The columns are an excellent choice for method optimization and parameter screening.
Cytiva HiScreen™ Sepharose™ Prepacked Fast Flow HIC Columns
Designed for method optimization and parameter screening
Cytiva HiScreen Capto™ L Columns
HiScreen Capto L columns are prepacked with Capto L, an affinity chromatography medium (resin) for capture of antibodies and antibody fragments such as Fab fragments, scFv, and Dabs.